Journal: Oncology Letters
Article Title: Upregulation of lncRNA GATA6-AS suppresses the migration and invasion of cervical squamous cell carcinoma by downregulating MTK-1
doi: 10.3892/ol.2019.10554
Figure Lengend Snippet: Effects of GATA6-AS overexpression on the migration and invasion of human cervical squamous cell carcinoma cell lines and normal cervical cell lines. (A) GATA6-AS expression levels were significantly higher in all cell lines following transfection. Exogenous expression of GATA6-AS inhibited the migration and invasion of the human cervical squamous cell carcinoma cell lines (B) SiHa and (C) C33A, but not the normal cervical cell lines (D) Ect1/E6E7 and (E) HCvEpC. *P<0.05. GATA6-AS, GATA binding protein 6 antisense; C, control; NC, negative control; Over, GATA6-AS overexpression.
Article Snippet: Therefore, the present study employed the two human cervical squamous cell carcinoma cell lines SiHa [HPV-positive; cat. no. HTB-35 TM , American Type Culture Collection (ATCC), Manassas, VA, USA] and C33A (HPV-negative; cat. no. HTB-31 TM ; ATCC), and the two normal cervical cell line; Ect1/E6E7 (HPV-positive; cat. no. CRL 2614 TM ; ATCC) and HCvEpC (HPV-negative; cat. no. 233-75a; Cell Applications, San Diego, CA, USA).
Techniques: Over Expression, Migration, Expressing, Transfection, Binding Assay, Control, Negative Control